Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633018 | 0.90 | KEAP1 (0.34) | KEAP1NFE2L2ALDH1A1MAPTKMT2A | |
| SCHEMBL6632994 | 0.86 | HTR1A (0.31) | — | |
| SCHEMBL6636006 | 0.85 | OXTR (0.32) | ALDH1A1KMT2A | |
| SCHEMBL6633881 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPTGAATSHR | |
| SCHEMBL6633485 | 0.81 | — | — | |
| SCHEMBL6634428 | 0.78 | ALDH1A1 (0.33) | ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL6632840 | 0.78 | TDP1 (0.32) | ALDH1A1MAPTGAA | |
| SCHEMBL6632832 | 0.78 | NCEH1 (0.31) | — | |
| SCHEMBL6633373 | 0.77 | HSD11B1 (0.33) | — | |
| SCHEMBL6633653 | 0.77 | HTR1A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |