Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634236 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1BTRPV1TAS1R3TAS1R1 | |
| SCHEMBL4858868 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MTNR1AMTNR1BTAS1R3TAS1R1 | |
| SCHEMBL14698658 | 0.71 | ALDH1A1 (0.83) | ALDH1A1MTNR1AMTNR1BTAS1R3TAS1R1 | |
| SCHEMBL30985347 | 0.71 | ALDH1A1 (0.83) | ALDH1A1MTNR1AMTNR1BTAS1R3TAS1R1 | |
| SCHEMBL4858887 | 0.71 | ALDH1A1 (0.83) | ALDH1A1MTNR1AMTNR1BTAS1R3TAS1R1 | |
| SCHEMBL4866618 | 0.71 | ALDH1A1 (0.83) | ALDH1A1MTNR1AMTNR1BTAS1R3TAS1R1 | |
| SCHEMBL4711698 | 0.68 | TRPV1 (0.53) | MTNR1AMTNR1BTRPV1LMNAUSP2 | |
| SCHEMBL16709695 | 0.67 | TRPV1 (0.52) | TRPV1LMNAUSP2TAS1R3TAS1R1 | |
| SCHEMBL27898825 | 0.67 | HSD17B2 (0.53) | ALDH1A1TRPV1 | |
| SCHEMBL53323 | 0.66 | ALDH1A1 (1.00) | ALDH1A1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047664-B1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-05-19 | — | — | EP | claimed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | claimed |
| EP-1047664-B1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |