Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22275810 | 0.84 | LTA4H (0.60) | L3MBTL1TAAR1LTA4HEPHX2MEN1 | |
| SCHEMBL5681870 | 0.80 | CA12 (0.75) | L3MBTL1LTA4HEPHX2CNR1MEN1 | |
| SCHEMBL20932231 | 0.80 | HPGD (0.57) | HTTTAAR1LTA4HEPHX2MEN1 | |
| SCHEMBL23083349 | 0.80 | TAAR1 (0.54) | TAAR1LTA4HEPHX2KMT2ACA1 | |
| SCHEMBL6635477 | 0.78 | MPO (0.63) | TAAR1LTA4HEPHX2CNR1CA1 | |
| SCHEMBL22275809 | 0.76 | HPGD (0.53) | HTTTAAR1LTA4HEPHX2MEN1 | |
| SCHEMBL19334423 | 0.76 | TSHR (0.67) | HTTLTA4HEPHX2CNR1MEN1 | |
| Bromide SCHEMBL20920820 | 0.75 | HPGD (0.52) | HTTTAAR1LTA4HEPHX2MEN1 | |
| SCHEMBL5574769 | 0.75 | LMNA (0.66) | HTTL3MBTL1TAAR1LTA4HEPHX2 | |
| SCHEMBL1568340 | 0.74 | ALDH1A1 (0.70) | HTTNPSR1L3MBTL1TAAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001056974-A2 | INHA INHIBITORS AND THEIR USE AS ANTIBACTERIALS | GENZYME CORPORATION (US) | 2001-08-09 | — | — | WO | claimed |
| US-6372752-B1 | ENZYME INHIBITORS, RESPIRATORY SYSTEM DISORDERS, TUBERCULOSIS AND MYCOBACTERIUM BACTERICIDES | GENZYME CORPORATION | 2002-04-16 | — | — | US | disclosed |
| WO-2001056974-A2 | INHA INHIBITORS AND THEIR USE AS ANTIBACTERIALS | GENZYME CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |