SCHEMBL6639714

SCHEMBL6639714

CCOC(=O)COc1ccnc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)n1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPOX P50336 3/20 0.41
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
PLA2G7 Q13093 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
P2RX3 P56373 1/20 0.32
CNR2 P34972 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6641762 0.92 LMNA (0.32) PPOX
SCHEMBL6636961 0.88 PPOX (0.41) PPOXPLA2G7
SCHEMBL6640534 0.85 BCAT1 (0.46) PPOX
SCHEMBL13843249 0.84 PPOX (0.46) PPOXGAAPKML3MBTL1MEN1
SCHEMBL121222 0.84 PPOX (0.41) PPOXGAAPKMPLA2G7L3MBTL1
SCHEMBL29351496 0.84 PPOX (0.41) PPOXGAAPKMPLA2G7L3MBTL1
SCHEMBL6638564 0.84 PLA2G7 (0.34) PKMPLA2G7MEN1KMT2A
SCHEMBL6638613 0.83 DHODH (0.34) PPOX
SCHEMBL23414181 0.83 PPOX (0.41) PPOXGAAPKMPLA2G7L3MBTL1
SCHEMBL6641269 0.83 BCAT1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP claimed
US-6537948-B1 Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-25 US claimed
EP-1122244-A1 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-08 EP claimed
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP disclosed