SCHEMBL66398

SCHEMBL66398

CCCC[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.42
MAPK1 P28482 1/20 0.42
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40
SLC1A3 P43003 1/20 0.40
CTSK P43235 6/20 0.39
CTSS P25774 1/20 0.39
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
CA1 P00915 2/20 0.37
MMP13 P45452 1/20 0.36
GRIK1 P39086 2/20 0.36
GRIK2 Q13002 2/20 0.36
PDF Q9HBH1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29696200 1.00 CA2 (0.42) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL66399 1.00 CA2 (0.42) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL31407436 0.95 GRIK1 (0.41) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL8460619 0.95 GRIK1 (0.41) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL25177958 0.94 GRIK1 (0.43) CA2SLC1A2SLC1A1MEN1KMT2A
SCHEMBL66573 0.90 HDAC1 (0.41) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL20826464 0.90 HDAC1 (0.41) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL67491 0.90 HDAC1 (0.41) CA2MAPK1SLC1A2SLC1A1SLC1A3
SCHEMBL27041531 0.87 MEN1 (0.37) MEN1GAAKMT2AMMP13
SCHEMBL27041525 0.87 MEN1 (0.37) MEN1GAAKMT2AMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
US-20250281433-A1 NOVEL DERIVATIVE COMPOUND HAVING BIPHENYL GROUP INTRODUCED INTO AMINO-ALKANOIC ACID AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME AMTIXBIO CO., LTD. (KR) 2025-09-11 US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
US-12180139-B2 Method for preparing aminoalkanoic acid derivative containing biphenyl group AMTIXBIO CO., LTD. (KR) 2024-12-31 US disclosed
US-12172945-B2 Aminoalkanoic acid derivative containing biphenyl group and use of the same AMTIXBIO CO., LTD. (KR) 2024-12-24 US disclosed
US-12129220-B2 Pharmaceutical composition comprising aminoalkanoic acid derivative containing biphenyl group AMTIXBIO CO., LTD. (KR) 2024-10-29 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
EP-3992177-B1 DERIVATIVE COMPOUND INTRODUCING BIPHENYL GROUP INTO NOVEL AMINOALKANOIC ACID AND ANTIFUNGAL PHARMACEUTICAL COMPOSITION COMPRISING SAME AMTIXBIO CO LTD (KR) 2024-05-08 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
EP-4268811-A1 NOVEL DERIVATIVE COMPOUND HAVING BIPHENYL GROUP INTRODUCED INTO AMINO-ALKANOIC ACID AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME Amtixbio Co., Ltd. (KR) 2023-11-01 EP disclosed
WO-2011149995-A1 NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA [C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS ABBOTT LABORATORIES (US) 2011-12-01 WO disclosed
US-20110281870-A1 NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS ABBOTT LABORATORIES (US) 2011-11-17 US disclosed
EP-2367790-A2 SUBSTITUTED OCTAHYDROCYCLOPENTA(C)PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS Abbott Laboratories (US) 2011-09-28 EP disclosed
WO-2010062927-A2 NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA(C)PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS ABBOTT LABORATORIES (US) 2010-06-03 WO disclosed
US-20100130558-A1 NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS ABBOTT LABORATORIES (US) 2010-05-27 US disclosed
EP-0266950-B1 Nor-statine and nor-cyclostatine polypeptides PFIZER (US) 1993-12-29 EP disclosed
US-5034376-A Nor-statine and nor-cyclostatine polypeptides PFIZER INC. (US) 1991-07-23 US disclosed
US-4935405-A Nor-statine and nor-cyclostatine polypeptides PFIZER INC. (US) 1990-06-19 US disclosed
US-4814342-A Nor-statine and nor-cyclostatine polypeptides PFIZER INC. (US) 1989-03-21 US disclosed
EP-0266950-A2 Nor-statine and nor-cyclostatine polypeptides PFIZER INC. (US) 1988-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12172945-B2 Aminoalkanoic acid derivative containing biphenyl group and use of the same GABBR1, AADAC, GABBR2 CA2 766/4885MAPK1 3514/4885SLC1A2 143/4885
US-20100130558-A1 NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS CACNA1C, ORAI1, CACNA1S CA2 138/4885MAPK1 1472/4885SLC1A2 234/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 CA2 1024/4885MAPK1 1980/4885SLC1A2 218/4885
US-20110281870-A1 NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS CACNA1C, ORAI1, CACNA1S CA2 138/4885MAPK1 1472/4885SLC1A2 234/4885
US-12180139-B2 Method for preparing aminoalkanoic acid derivative containing biphenyl group AKR7A2, CYP51A1, APEH CA2 1098/4885MAPK1 3918/4885SLC1A2 249/4885
US-20250281433-A1 NOVEL DERIVATIVE COMPOUND HAVING BIPHENYL GROUP INTRODUCED INTO AMINO-ALKANOIC ACID AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME AADAT, AADAC, AHR CA2 1311/4885MAPK1 1755/4885SLC1A2 510/4885
US-12129220-B2 Pharmaceutical composition comprising aminoalkanoic acid derivative containing biphenyl group AHR, AADAC, GABBR1 CA2 852/4885MAPK1 4069/4885SLC1A2 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.