Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500060 | 0.83 | ALDH1A1 (0.51) | FOLH1LDHAPTPN1MCL1HDAC7 | |
| SCHEMBL6637829 | 0.83 | ACLY (0.46) | SMN1; SMN2MEN1KMT2AFOLH1PTPN1 | |
| SCHEMBL27967819 | 0.81 | LDHA (0.46) | SMN1; SMN2MEN1KMT2AFOLH1LDHA | |
| SCHEMBL6641207 | 0.79 | FABP4 (0.45) | SMN1; SMN2MEN1KMT2AFOLH1PTPN1 | |
| SCHEMBL27532813 | 0.78 | LDHA (0.53) | FOLH1LDHAPTPN1MCL1HDAC7 | |
| SCHEMBL6637362 | 0.77 | PRKAB2 (0.48) | MEN1KMT2AFOLH1LDHAPTPN1 | |
| SCHEMBL667582 | 0.76 | PTPN1 (0.59) | FOLH1PTPN1MCL1HDAC7HNF4A | |
| SCHEMBL10697549 | 0.76 | KDM4E (0.50) | SMN1; SMN2ALDH1A1TP53GAAMAPT | |
| SCHEMBL9171492 | 0.74 | PTPN1 (0.57) | FOLH1PTPN1MCL1HDAC7HNF4A | |
| SCHEMBL28804822 | 0.74 | LDHA (0.57) | FOLH1LDHAPTPN1MCL1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |