Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 3/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6640643 | 0.87 | CPB2 (0.46) | CPB2EPHX2PPARGCDC7DBF4 | |
| SCHEMBL27231720 | 0.81 | EPHX2 (0.52) | CPB2EPHX2PPARGCDC7DBF4 | |
| SCHEMBL6779373 | 0.76 | SLC1A3 (0.44) | TRPM8MAPTPKMCETP | |
| SCHEMBL2672559 | 0.75 | MMP8 (0.54) | CDC7DBF4NAMPTMAPTPKM | |
| SCHEMBL5314193 | 0.73 | CYP1A2 (0.48) | CDC7DBF4NAMPTMAPTPKM | |
| SCHEMBL2958476 | 0.73 | ALDH1A1 (0.50) | EPHX2PPARGCDC7DBF4NAMPT | |
| SCHEMBL5570673 | 0.73 | CYP3A4 (0.45) | POLBMAPTCYP19A1KMT2A | |
| SCHEMBL2370593 | 0.72 | CYP19A1 (0.45) | CDC7DBF4NAMPTMAPTCYP19A1 | |
| SCHEMBL20543397 | 0.71 | SCN9A (0.39) | TRPM8MAPTCETP | |
| SCHEMBL1127510 | 0.71 | SMN1; SMN2 (0.46) | TRPM8PKMGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757685-B1 | NOVEL ACYCLIC AND CYCLIC AMIDES AS NEUROTRANSMITTER RELEASE ENHANCERS | PFIZER (US) | 2004-07-21 | — | — | EP | disclosed |
| US-5854232-A | Acyclic anc cyclic amides as neurotransmitter release enhancers | PFIZER INC. (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0757685-A1 | NOVEL ACYCLIC AND CYCLIC AMIDES AS NEUROTRANSMITTER RELEASE ENHANCERS | PFIZER INC. (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029909-A1 | NOVEL ACYCLIC AND CYCLIC AMIDES AS NEUROTRANSMITTER RELEASE ENHANCERS | PFIZER INC. (US) | 1995-11-09 | — | — | WO | disclosed |