Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.52 |
| ▸ | HTR2C | P28335 | 7/20 | 0.52 |
| ▸ | HTR2B | P41595 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MTTP | P55157 | 2/20 | 0.42 |
| ▸ | APOB | P04114 | 1/20 | 0.42 |
| ▸ | SRPK1 | Q96SB4 | 5/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.41 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643318 | 0.89 | HTR2A (0.55) | HTR2AHTR2CHTR2BSMOMTTP | |
| SCHEMBL6645705 | 0.89 | SMN1; SMN2 (0.50) | HTR2AHTR2CHTR2BSMOMAPT | |
| SCHEMBL6646057 | 0.88 | HTR2C (0.50) | HTR2AHTR2CHTR2BMAPTSMN1; SMN2 | |
| SCHEMBL6646675 | 0.88 | GAA (0.46) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6645864 | 0.88 | GAA (0.46) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6646117 | 0.88 | MAPT (0.48) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6646377 | 0.87 | HTR2A (0.55) | HTR2AHTR2CHTR2BSMOMTTP | |
| SCHEMBL6648311 | 0.87 | SMN1; SMN2 (0.45) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6664848 | 0.87 | HTR2A (0.53) | HTR2AHTR2CHTR2BSMOMTTP | |
| SCHEMBL6645134 | 0.87 | HTR2A (0.53) | HTR2AHTR2CHTR2BSMOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | HTR2A 855/4885HTR2C 1349/4885HTR2B 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.