Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645353 | 0.86 | THRB (0.51) | MAPTSMN1; SMN2ALDH1A1RAB9AKDM4E | |
| SCHEMBL6646958 | 0.85 | ALDH1A1 (0.45) | MAPTSMN1; SMN2ALDH1A1RAB9AKDM4E | |
| SCHEMBL6647133 | 0.81 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2ALDH1A1RAB9AKDM4E | |
| SCHEMBL6645983 | 0.78 | ALDH1A1 (0.46) | MAPTSMN1; SMN2ALDH1A1RAB9AKDM4E | |
| SCHEMBL6645303 | 0.77 | THRB (0.48) | MAPTALDH1A1RAB9AKDM4ETSHR | |
| SCHEMBL6647954 | 0.76 | ALDH1A1 (0.47) | MAPTSMN1; SMN2ALDH1A1RAB9ATSHR | |
| SCHEMBL6644574 | 0.76 | KDR (0.46) | MAPTSMN1; SMN2ALDH1A1RAB9AKDM4E | |
| SCHEMBL6647631 | 0.72 | APOB (0.47) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL6647724 | 0.72 | THRB (0.48) | ALDH1A1LMNAPOLBGAA | |
| SCHEMBL26434280 | 0.71 | LMNA (0.57) | MAPTSMN1; SMN2ALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | MAPT 4101/4885SMN1; SMN2 1836/4885ALDH1A1 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.