Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645289 | 0.88 | MAPT (0.37) | ALDH1A1MAPTPOLBL3MBTL1KDM4E | |
| SCHEMBL6645258 | 0.86 | ALDH1A1 (0.36) | ALDH1A1MAPTPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL6645806 | 0.84 | MAPT (0.34) | ALDH1A1MAPTSMN1; SMN2TP53PTPN11 | |
| SCHEMBL6647070 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBNPSR1L3MBTL1 | |
| SCHEMBL6649241 | 0.80 | THRB (0.48) | ALDH1A1MAPTPOLBNPSR1L3MBTL1 | |
| SCHEMBL6648598 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBNPSR1L3MBTL1 | |
| SCHEMBL6645107 | 0.79 | KCNA5 (0.39) | ALDH1A1MAPTPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL6644382 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBNPSR1L3MBTL1 | |
| SCHEMBL6646095 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL6648929 | 0.77 | TAS1R3 (0.42) | ALDH1A1MAPTPOLBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | ALDH1A1 2174/4885MAPT 4101/4885POLB 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.