Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686235 | 0.75 | ALOX15 (0.32) | MAPK8 | |
| SCHEMBL27747320 | 0.71 | MPO (0.39) | — | |
| SCHEMBL4826385 | 0.68 | — | — | |
| SCHEMBL5606524 | 0.67 | CES2 (0.50) | — | |
| SCHEMBL6687438 | 0.66 | RORB (0.33) | L3MBTL1 | |
| SCHEMBL4831103 | 0.66 | NPSR1 (0.30) | — | |
| SCHEMBL6440646 | 0.64 | GRIK1 (0.44) | — | |
| SCHEMBL28217598 | 0.64 | PTGIR (0.46) | — | |
| SCHEMBL7621277 | 0.64 | MEN1 (0.41) | — | |
| SCHEMBL27721413 | 0.64 | P2RX1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487841-A1 | THIOPYRIMIDINE AND ISOTHIAZOLOPYRIMIDINE KINASE INHIBITORS | Abbott Laboratories (US) | 2004-12-22 | — | — | EP | claimed |
| WO-2003080625-A1 | THIOPYRIMIDINE AND ISOTHIAZOLOPYRIMIDINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-10-02 | — | — | WO | claimed |