SCHEMBL332300

SCHEMBL332300

CC(S)c1cccc(C(C)S)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 3/20 0.37
HDAC8 Q9BY41 3/20 0.37
HDAC2 Q92769 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MDM4 O15151 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
TYR P14679 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
CA5A P35218 1/20 0.37
HTT P42858 1/20 0.37
MDM2 Q00987 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20273069 0.92 HDAC4 (0.47) HDAC4HDAC8HDAC2KDM4EMDM4
SCHEMBL25091414 0.90 PGK1 (0.39) HDAC4HDAC8HDAC2KDM4EMDM4
SCHEMBL28648350 0.85 HDAC4 (0.32) HDAC4HDAC8HDAC2KDM4EMDM4
SCHEMBL28763530 0.83 ALDH1A1 (0.44) ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL27486267 0.83 SLC6A3 (0.36) HDAC4HDAC8HDAC2KDM4EMDM4
SCHEMBL24810440 0.83 ACHE (0.44) HDAC4
SCHEMBL8468025 0.83 CYP3A4 (0.48) KDM4EALDH1A1CA1CA2TP53
SCHEMBL17550749 0.83 ACHE (0.44) HDAC4
SCHEMBL331382 0.81
SCHEMBL24810036 0.79 CASR (0.50) ALDH1A1CA1CA2CYP3A4CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12275813-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2025-04-15 US claimed
EP-3581600-B1 RESIN LENS AND PREPARATION METHOD THEREFOR EFIRM NEW MAT CO LTD (CN) 2025-01-08 EP claimed
US-11548971-B2 Method for producing a resin lens from a polyisocyanate and release agent at reduced pressure YIFENG NEW MATERIALS CO., LTD. (CN) 2023-01-10 US claimed
US-11402755-B2 Chemically amplified positive-type photosensitive resin composition, method for manufacturing substrate with template, and method for manufacturing plated article TOKYO OHKA KOGYO CO., LTD. (JP) 2022-08-02 US claimed
US-20210221940-A1 RESIN LENS AND METHOD FOR PRODUCING THE SAME SHANDONG EFIRM BIOCHEMISTRY AND ENVIRONMENTAL PROTECTION CO., LTD. (CN) 2021-07-22 US claimed
EP-2963457-B1 OPTICAL MATERIAL, COMPOSITION FOR USE THEREIN, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2018-07-11 EP claimed
US-6391433-B1 None US disclosed
WO-2026105644-A1 ISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS 三井化学株式会社 2026-05-21 WO disclosed
WO-2026105643-A1 ISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS 三井化学株式会社 2026-05-21 WO disclosed
US-12606692-B2 Spectacle lens HOYA LENS THAILAND LTD. (TH) 2026-04-21 US disclosed
EP-4725987-A2 XYLYLENE DIISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS TECHNICAL FIELD Mitsui Chemicals, Inc. (JP) 2026-04-15 EP disclosed
US-20260062512-A1 CURABLE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT KUREHA CORPORATION (JP) 2026-03-05 US disclosed
US-20260062548-A1 RUBBER-BONDED CELLULOSE FIBERS AND MANUFACTURING METHOD THEREFOR, RESIN COMPOSITION AND MANUFACTURING METHOD THEREFOR, AND CURABLE RESIN COMPOSITION KUREHA CORPORATION (JP) 2026-03-05 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0374258-A1 HIGH REFRACTIVE INDEX LENS AND METHOD FOR ITS PRODUCTION MITSUI CHEMICALS, INC. (JP) 1990-06-27 EP disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0050261-B1 MOULDING MASSES STABILIZED AGAINST THERMOLYSIS WITH A LOW MONOMER CONTENT BAYER AG (DE) 1985-08-14 EP disclosed
EP-0050261-A1 Moulding masses stabilized against thermolysis with a low monomer content BAYER AG (DE) 1982-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062548-A1 RUBBER-BONDED CELLULOSE FIBERS AND MANUFACTURING METHOD THEREFOR, RESIN COMPOSITION AND MANUFACTURING METHOD THEREFOR, AND CURABLE RESIN COMPOSITION CROCC, WASF2, DCXR HDAC4 2030/4885HDAC8 2048/4885HDAC2 2944/4885
US-12606692-B2 Spectacle lens POT1, TCOF1, CRY1 HDAC4 4790/4885HDAC8 4653/4885HDAC2 4009/4885
US-20260062512-A1 CURABLE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT EHMT1, EHMT2, ASH2L HDAC4 477/4885HDAC8 1232/4885HDAC2 731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.