SCHEMBL6650593

SCHEMBL6650593

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ccc(C#N)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA4 P43681 1/20 0.42
GPR119 Q8TDV5 2/20 0.40
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
ABCB1 P08183 7/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
PGR P06401 1/20 0.37
KIF11 P52732 1/20 0.37
AR P10275 1/20 0.37
MLYCD O95822 1/20 0.36
EGLN2 Q96KS0 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22529835 0.92 CHRNB2 (0.39) CHRNB2CHRNB4CHRNA3CHRNA4GPR119
SCHEMBL27699057 0.86 CHRNB2 (0.36) CHRNB2CHRNB4CHRNA3CHRNA4GPR119
SCHEMBL3868314 0.85 CHRNB2 (0.41) CHRNB2CHRNB4CHRNA3CHRNA4GPR119
SCHEMBL4889483 0.84 EGLN2 (0.37) CHRNB2CHRNB4CHRNA3CHRNA4GPR119
SCHEMBL20534746 0.83 CHRNB2 (0.45) CHRNB2CHRNB4CHRNA3CHRNA4GPR119
SCHEMBL38651897 0.81 MLYCD (0.50) CHRNB2CHRNB4CHRNA3CHRNA4GPR119
SCHEMBL19418096 0.81 CHRNB2 (0.41) CHRNB2CHRNB4CHRNA3CHRNA4GPR119
SCHEMBL1008386 0.81 PDK1 (0.40) ABCB1ALDH1A1MAPTKMT2A
SCHEMBL20534652 0.80 CHRNB2 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4GPR119
SCHEMBL14266578 0.79 MLYCD (0.43) CHRNB2CHRNB4CHRNA3CHRNA4GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486240-B2 Oxadiazole compounds for controlling or preventing phytopathogenic fungi PI INDUSTRIES LTD. (IN) 2025-12-02 US disclosed
EP-3953340-B1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD (IN) 2023-08-02 EP disclosed
US-20220135531-A1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2022-05-05 US disclosed
EP-3953340-A1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI PI Industries Ltd. (IN) 2022-02-16 EP disclosed
EP-1482940-A2 PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE Pharmacia Corporation (US) 2004-12-08 EP disclosed
US-20040082585-A1 Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade PHARMACIA CORPORATION 2004-04-29 US disclosed
WO-2003028729-A2 PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE PHARMACIA CORPORATION (US) 2003-04-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486240-B2 Oxadiazole compounds for controlling or preventing phytopathogenic fungi OXA1L, CYP51A1, ERG28 CHRNB2 4799/4885CHRNB4 4798/4885CHRNA3 4040/4885
US-20220135531-A1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI OXA1L, FBXL19, ERG28 CHRNB2 4827/4885CHRNB4 4832/4885CHRNA3 4385/4885
US-20040082585-A1 Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade TFPI, F2, PLG CHRNB2 4852/4885CHRNB4 4840/4885CHRNA3 4855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.