Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648998 | 0.76 | ALDH1A1 (0.43) | MAPTKMT2AALOX5ERBB2HSP90AA1 | |
| SCHEMBL6649786 | 0.72 | ALOX5 (0.41) | KMT2AALOX5ERBB2HSP90AA1HSP90AB1 | |
| SCHEMBL5612102 | 0.71 | HSPA5 (0.43) | MAPTALDH1A1HPGD | |
| SCHEMBL4909294 | 0.70 | SMN1; SMN2 (0.43) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL16815266 | 0.68 | SLC9A1 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL6657762 | 0.68 | MEN1 (0.34) | MAPTKMT2ALMNAMEN1KDM4E | |
| SCHEMBL6650791 | 0.67 | P2RX7 (0.40) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL13500287 | 0.67 | SLC9A1 (0.39) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13212232 | 0.66 | SLC9A1 (0.41) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL20742274 | 0.65 | SLC9A1 (0.38) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |