Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | IAPP | P10997 | 1/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612102 | 0.78 | HSPA5 (0.43) | ALDH1A1ESR1CNR2MAPTSLC9A1 | |
| SCHEMBL16815266 | 0.69 | SLC9A1 (0.38) | KMT2AALDH1A1ESR1DGAT1GRM2 | |
| SCHEMBL11444820 | 0.69 | GABRA1 (0.61) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL25660388 | 0.68 | SLC9A1 (0.37) | MEN1KMT2AALDH1A1ESR1LMNA | |
| SCHEMBL6650868 | 0.68 | MAPT (0.39) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL13500287 | 0.67 | SLC9A1 (0.39) | MEN1KMT2AALDH1A1ESR1MAPT | |
| SCHEMBL2494852 | 0.67 | SLC9A1 (0.36) | ALDH1A1LMNAKDM4EMAPTSLC9A1 | |
| SCHEMBL7087827 | 0.67 | ALOX5 (0.37) | MEN1KMT2AALDH1A1ESR1LMNA | |
| SCHEMBL13212232 | 0.67 | SLC9A1 (0.41) | MEN1KMT2AALDH1A1ESR1KDM4E | |
| SCHEMBL20742274 | 0.66 | SLC9A1 (0.38) | KMT2AALDH1A1ESR1DGAT1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |