Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651087 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNACES2CES1ALKBH5 | |
| SCHEMBL4866555 | 0.80 | CES2 (0.41) | ALDH1A1CES2CES1TSHRHDAC8 | |
| SCHEMBL4866559 | 0.80 | CES2 (0.41) | ALDH1A1CES2CES1TSHRHDAC8 | |
| SCHEMBL8536055 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNACES2CES1ALKBH5 | |
| SCHEMBL2400052 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNACES2CES1ALKBH5 | |
| SCHEMBL8209830 | 0.70 | CES2 (0.48) | ALDH1A1CES2CES1TSHRHDAC8 | |
| SCHEMBL3991168 | 0.70 | ALDH1A1 (0.47) | ALDH1A1LMNACES2CES1ALKBH5 | |
| Succinic Acid SCHEMBL27494088 | 0.68 | LMNA (0.75) | ALDH1A1LMNAALKBH5SUCNR1EGLN1 | |
| Succinic Acid SCHEMBL27617119 | 0.68 | LMNA (0.75) | ALDH1A1LMNAALKBH5SUCNR1EGLN1 | |
| Succinic Acid SCHEMBL28567889 | 0.68 | ALDH1A1 (0.54) | ALDH1A1LMNACES2CES1ALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828464-B2 | Preparation of cyclopentenones | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-07 | — | — | US | disclosed |
| US-20040102655-A1 | Preparation of cyclopentenoes | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-27 | — | — | US | disclosed |
| EP-1422212-A1 | Process for preparing cyclopentenone | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-26 | — | — | EP | disclosed |
| EP-0297447-B1 | METHOD FOR THE PREPARATION OF 2-CYCLOPENTENONES | BASF Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | disclosed |
| EP-0297447-A2 | Method for the preparation of 2-cyclopentenones | BASF Aktiengesellschaft (DE) | 1989-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102655-A1 | Preparation of cyclopentenoes | CYP17A1, CYP2F1, CYP2S1 | ALDH1A1 389/4885LMNA 3150/4885CES2 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.