Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651329 | 0.93 | LTB4R (0.44) | LTB4RKMT2AALDH1A1MAP2K1FAAH | |
| SCHEMBL9212284 | 0.77 | ALDH1A1 (0.43) | LTB4RKMT2AALDH1A1MAPK14RAB9A | |
| SCHEMBL8377107 | 0.74 | CYP1A2 (0.39) | LTB4RALDH1A1MAPK14HSD17B10LMNA | |
| SCHEMBL6952286 | 0.73 | CLK1 (0.50) | LTB4RALDH1A1RAB9AHSD17B10NPC1 | |
| SCHEMBL8377115 | 0.69 | MEN1 (0.37) | LTB4RKMT2AALDH1A1MEN1MAPK14 | |
| SCHEMBL15148171 | 0.69 | LTB4R (0.47) | LTB4RKMT2AALDH1A1MEN1MAPK14 | |
| SCHEMBL16576447 | 0.69 | MAOB (0.44) | KMT2AALDH1A1MEN1RAB9ASMN1; SMN2 | |
| SCHEMBL21596857 | 0.69 | HTR3A (0.47) | LTB4RKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL6089216 | 0.67 | MAPT (0.51) | LTB4RKMT2AALDH1A1MEN1MAPK14 | |
| SCHEMBL15145315 | 0.67 | LTB4R (0.49) | LTB4RALDH1A1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448534-A1 | 6-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OFTHE COAGULATION CASCADE | Pharmacia Corporation (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003029224-A1 | 6-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |