Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892797 | 0.88 | DRD2 (0.58) | DRD2DRD1DRD4DRD5HTR7 | |
| SCHEMBL6651166 | 0.83 | KDM4E (0.38) | DRD2DRD1DRD4DRD5HTR7 | |
| SCHEMBL6650105 | 0.81 | NR4A2 (0.42) | DRD2DRD1DRD4DRD5P2RX7 | |
| Citric Acid SCHEMBL8657218 | 0.75 | KDM4E (0.70) | DRD2DRD1DRD4DRD5HRH1 | |
| SCHEMBL4303080 | 0.73 | HTR7 (0.36) | DRD2DRD1DRD4DRD5HTR7 | |
| SCHEMBL4909282 | 0.73 | KAT2B (0.34) | DRD2DRD1DRD4DRD5HTR7 | |
| SCHEMBL6650106 | 0.72 | P2RX7 (0.46) | DRD4P2RX7KDM4EALDH1A1LMNA | |
| SCHEMBL19471246 | 0.72 | P2RX7 (0.38) | P2RX7KDM4EALDH1A1LMNA | |
| SCHEMBL7755878 | 0.72 | LTA4H (0.56) | CHRNB2CHRNA4 | |
| SCHEMBL5599334 | 0.70 | ADRB2 (0.35) | DRD2DRD1DRD4DRD5HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |