Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978531 | 0.87 | SMN1; SMN2 (0.36) | HTTMAPTKDM4ETP53GAA | |
| SCHEMBL6650625 | 0.83 | MEN1 (0.35) | HTTMAPTKDM4EHSD17B10POLB | |
| SCHEMBL6651346 | 0.81 | L3MBTL1 (0.36) | MAPTKDM4ETP53HSD17B10POLB | |
| SCHEMBL10102407 | 0.81 | KDM4E (0.33) | HTTMAPTKDM4ETP53GAA | |
| SCHEMBL12952422 | 0.80 | CYP3A4 (0.30) | CYP3A4 | |
| SCHEMBL5157934 | 0.80 | GABRA1 (0.33) | HTTMAPTKDM4EGAAHSD17B10 | |
| SCHEMBL15254539 | 0.79 | KDM4E (0.39) | HTTMAPTKDM4ETP53TSHR | |
| SCHEMBL17929223 | 0.78 | KDM4E (0.39) | MAPTKDM4ETP53HSD17B10POLB | |
| SCHEMBL5158212 | 0.78 | MAPT (0.43) | HTTMAPTKDM4ETP53GAA | |
| SCHEMBL5159928 | 0.78 | NCEH1 (0.32) | HTTMAPTKDM4ETP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1248778-B1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2004-06-16 | — | — | EP | claimed |
| US-6340766-B1 | PHOTOCHROMIC DYES ON SUBSTRATES LIKE GLASS WITH PROTECTIVE COATINGS | TRANSITION OPTICAL, INC. | 2002-01-22 | — | — | US | claimed |
| US-20020007078-A1 | Novel substituted naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2002-01-17 | — | — | US | claimed |
| EP-1248778-B1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6340766-B1 | PHOTOCHROMIC DYES ON SUBSTRATES LIKE GLASS WITH PROTECTIVE COATINGS | TRANSITION OPTICAL, INC. | 2002-01-22 | — | — | US | disclosed |
| US-20020007078-A1 | Novel substituted naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007078-A1 | Novel substituted naphthopyrans | CRYZ, NR2E3, UACA | HTT 2179/4885MAPT 1279/4885KDM4E 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.