Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | BRD2 | P25440 | 2/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561 | 0.85 | LPAR1 (0.34) | RAB9ASMN1; SMN2EDNRBEDNRANPC1 | |
| SCHEMBL6698 | 0.83 | MEN1 (0.38) | MEN1KMT2ARAB9AHPGDNPSR1 | |
| SCHEMBL6697 | 0.79 | MTNR1A (0.40) | MEN1KMT2ARAB9AHPGDNPSR1 | |
| SCHEMBL20425444 | 0.78 | MTNR1A (0.42) | KMT2ARAB9AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL11409 | 0.74 | TP53 (0.31) | TP53EDNRBEDNRABRD4TDP1 | |
| SCHEMBL6651 | 0.73 | MAPT (0.41) | MEN1KMT2AHPGDMTNR1AMTNR1B | |
| SCHEMBL1933 | 0.72 | EPHX1 (0.34) | MEN1KMT2ARAB9AHPGDTP53 | |
| SCHEMBL7689 | 0.71 | CYP1A2 (0.31) | TDP1 | |
| SCHEMBL1448 | 0.71 | BRD4 (0.35) | MEN1KMT2ARAB9AHPGDNPSR1 | |
| SCHEMBL2762295 | 0.71 | FPR2 (0.40) | MEN1KMT2ARAB9AHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |