Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 2/20 | 0.34 |
| ▸ | ADH1A | P07327 | 2/20 | 0.34 |
| ▸ | ADH7 | P40394 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473716 | 0.82 | TAAR1 (0.62) | CNR1TAAR1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2471353 | 0.79 | LMNA (0.65) | CNR1LMNATAAR1KMT2ASMN1; SMN2 | |
| SCHEMBL350370 | 0.78 | ADH1B (0.50) | LMNAADH1BADH1AADH7IDO1 | |
| Hydrochloric Acid SCHEMBL3341451 | 0.77 | ADH1B (0.48) | LMNAADH1BADH1AADH7IDO1 | |
| SCHEMBL7335595 | 0.76 | DAO (0.40) | CNR1TAAR1DAOCYP3A4CHRM2 | |
| SCHEMBL9320730 | 0.75 | LTA4H (0.43) | LMNACYP3A4ADH1BADH1AADH7 | |
| SCHEMBL8763412 | 0.75 | LMNA (0.50) | LMNATAAR1SMN1; SMN2ADH1BADH1A | |
| SCHEMBL21540799 | 0.75 | SIGMAR1 (0.59) | LMNATAAR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5281680 | 0.71 | TAAR1 (0.64) | CNR1LMNATAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2355446 | 0.71 | TSHR (0.57) | CNR1TAAR1ALDH1A1DAOCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423117-A1 | 2-SUBSTITUTED 1-ARYLPIPERAZINES AS TACHYKININ ANTAGONISTS AND/OR SEROTONIN REUPTAKE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003015784-A1 | 2-SUBSTITUTED 1-ARYLPIPERAZINES AS TACHYKININ ANTAGONISTS AND/OR SEROTONIN REUPTAKE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-02-27 | — | — | WO | disclosed |