Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30293692 | 0.91 | KDM4E (0.54) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL28948110 | 0.91 | KDM4E (0.54) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL6653306 | 0.89 | MAPT (0.60) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL6651692 | 0.88 | ALOX15 (0.55) | MAPTHPGDMAOBKDM4EALDH1A1 | |
| SCHEMBL6651695 | 0.88 | ALOX15 (0.55) | MAPTHPGDMAOBKDM4EALDH1A1 | |
| SCHEMBL5384385 | 0.88 | MAOB (0.55) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL3901893 | 0.81 | ALOX5 (0.58) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL18614861 | 0.81 | GAA (0.70) | MAPTHPGDMEN1LMNAKMT2A | |
| SCHEMBL28964412 | 0.81 | ALOX5 (0.55) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL6650885 | 0.81 | MTNR1A (0.58) | MAPTHPGDMAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875501-B1 | Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| EP-0796847-B1 | Pyridine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO LTD (JP) | 2001-11-28 | — | — | EP | disclosed |
| EP-0802196-B1 | Alkylenediamine derivatives as drugs for the treatment of ulcers and the inhibition of Helicobacter pylori | SHISEIDO CO LTD (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6043243-A | Pyrrolidine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| US-6017937-A | BACTERICIDE AGAINST HELICOBACTER PYROLI; INHIBITING ACID SECRETION IN STOMACH OF MAN OR MAMMALS, PREVENTING OR CURING ULCER | SHISEIDO CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-6001880-A | DISUBSTITUTED N-(2-DIALKYLAMINOETHYL)BENZAMIDE DERIVATIVES OF GIVEN FORMULA; ANTIBACTERIAL ACTIVITY AGAINST HELICOBACTER PYROLI, ADMINISTERING FOR THE PREVENTION OR CURE OF PEPTIC ULCERS | SHISEIDO CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5925667-A | INHIBITS GROWTH OF HELICOBACTER PYLORI | SHISEIDO CO., LTD. (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5859032-A | HAVING ANTIBACTERIAL ACTIVITY AGAINST HELICOBACTER PYLORI | SHISEIDO CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0875501-A2 | Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1998-11-04 | — | — | EP | disclosed |
| EP-0869118-A1 | Pyrrolidine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5814634-A | PEPTIC ULCERS, GASTRIC ULCERS | SHISEIDO CO. LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0802196-A1 | Alkylenediamine derivative, antiulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0796847-A1 | Pyridine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1997-09-24 | — | — | EP | disclosed |