Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 6/20 | 1.00 |
| ▸ | GPR55 | Q9Y2T6 | 7/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | CEL | P19835 | 4/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27429798 | 0.69 | CTRC (0.53) | CTRCGPR55CNR2NR1H2 | |
| SCHEMBL29709847 | 0.68 | GPR55 (0.68) | CTRCGPR55 | |
| SCHEMBL19331106 | 0.68 | GPR55 (0.68) | CTRCGPR55 | |
| SCHEMBL28412953 | 0.67 | ELANE (0.53) | CTRCNR1H2ELANE | |
| SCHEMBL8098213 | 0.66 | CALM1 (0.55) | CTRCGPR55CNR2 | |
| SCHEMBL972711 | 0.65 | CALM1 (0.69) | MEN1KMT2A | |
| SCHEMBL11403614 | 0.65 | CALM1 (0.52) | CTRCNR1H2MEN1KMT2A | |
| SCHEMBL4423210 | 0.65 | SIGMAR1 (0.53) | CTRCMEN1KMT2A | |
| SCHEMBL2861971 | 0.64 | CTRC (0.47) | CTRCNR1H2MEN1KMT2A | |
| SCHEMBL160386 | 0.64 | BCL2 (0.48) | CTRCGPR55CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323715-B1 | Inhibitors of cholesterol esterase | UNIV NEW MEXICO (US) | 2004-06-30 | — | — | EP | disclosed |
| EP-0975617-B1 | INHIBITORS OF CHOLESTEROL ESTERASE | UNIV NEW MEXICO (US) | 2003-11-05 | — | — | EP | disclosed |
| EP-1323715-A1 | Inhibitors of cholesterol esterase | The University of New Mexico (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-0975617-A4 | INHIBITORS OF CHOLESTEROL ESTERASE | UNIV NEW MEXICO (US) | 2000-09-13 | — | — | EP | disclosed |
| US-6114545-A | Inhibitors of cholesterol esterase | UNIVERSITY OF NEW MEXICO (US) | 2000-09-05 | — | — | US | disclosed |
| US-6034255-A | Inhibitors of cholesterol esterase | UNIVERSITY OF NEW MEXICO (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0975617-A1 | INHIBITORS OF CHOLESTEROL ESTERASE | The University of New Mexico (US) | 2000-02-02 | — | — | EP | disclosed |
| US-5942631-A | Inhibitors of cholesterol esterase | UNIVERSITY OF NEW MEXICO (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1998046585-A1 | INHIBITORS OF CHOLESTEROL ESTERASE | THE UNIVERSITY OF NEW MEXICO (US) | 1998-10-22 | — | — | WO | disclosed |