SCHEMBL2861971

SCHEMBL2861971

Clc1ccc(Cc2ccccc2)c(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 3/20 0.47
CALM1 P0DP23 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
BCL2 P10415 1/20 0.43
BCL2L1 Q07817 1/20 0.43
ALOX5 P09917 1/20 0.42
NR1H2 P55055 1/20 0.42
FEN1 P39748 1/20 0.42
HTR2A P28223 1/20 0.41
ALDH1A1 P00352 1/20 0.38
P2RX7 Q99572 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3301733 0.83 PNMT (0.56) CTRCCALM1MEN1KMT2ACYP3A4
SCHEMBL4465598 0.81 CYP3A4 (0.43) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL11403614 0.79 CALM1 (0.52) CTRCCALM1MEN1KMT2ACYP3A4
SCHEMBL28135147 0.77 CTRC (0.40) CTRCCALM1MEN1KMT2ACYP3A4
SCHEMBL11520705 0.76 PNMT (0.58) MEN1KMT2ACYP3A4ALDH1A1P2RX7
SCHEMBL27538653 0.75 CTRC (0.49) CTRCCALM1MEN1KMT2ACYP3A4
SCHEMBL10732241 0.75 LTA4H (0.44) CTRCALDH1A1
SCHEMBL4423210 0.75 SIGMAR1 (0.53) CTRCCALM1MEN1KMT2ACYP3A4
Ammonia Solution, Strong SCHEMBL3291590 0.74 CTRC (0.47) CTRCCALM1MEN1KMT2ACYP3A4
SCHEMBL10817061 0.74 CYP2A6 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115403461-B Method for synthesizing benzoic acid by oxidizing ethylbenzene 吕梁学院 2023-09-22 CN disclosed
CN-115403461-A Method for synthesizing benzoic acid by oxidizing ethylbenzene 吕梁学院 2022-11-29 CN disclosed
CN-109970544-B Device and method for preparing benzoic acid from toluene 中北大学 2021-07-02 CN disclosed
CN-110026145-B Hypergravity reaction device and application thereof 中北大学 2021-05-18 CN disclosed
WO-2010016620-A1 SURFACE TREATING AGENT FOR COPPER OR COPPER ALLOY AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2010-02-11 WO disclosed