Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521212 | 0.94 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL11695056 | 0.93 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL14596279 | 0.90 | ALDH1A1 (0.69) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL29740663 | 0.85 | ALDH1A1 (0.82) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL33801 | 0.80 | TDP1 (0.67) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL8467252 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL33781 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL6822008 | 0.79 | ALDH1A1 (0.79) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL4717774 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL970320 | 0.78 | ALDH1A1 (0.95) | ALDH1A1TSHRMAPK1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340596-B1 | COLORIMETRIC ANALYSIS; REACTING HYDROGEN SULFIDE WITH P-(DIALKYLAMINO)-ANILINE DERIVATIVE AND OXIDIZING AGENT UNDER ACIDIC CONDITIONS | FUJIREBIO INC. (JP) | 2002-01-22 | — | — | US | claimed |
| EP-1265846-B1 | IMPROVED SYNTHESIS OF N,N-DISUBSTITUTED-p-PHENYLENEDIAMINE | ANTICANCER INC (US) | 2004-06-23 | — | — | EP | disclosed |
| US-6448446-B1 | ONCE THE PRODUCT DSPDA OR ITS SALT IS FORMED, OXYGEN MUST BE EXCLUDED FROM ALL MANIPULATIONS. | ANTICANCER, INC. | 2002-09-10 | — | — | US | disclosed |
| US-20020026080-A1 | Synthesis of N,N-disubstituted-p-phenylenediamine | ANTICANCER, INC. | 2002-02-28 | — | — | US | disclosed |
| US-6340596-B1 | COLORIMETRIC ANALYSIS; REACTING HYDROGEN SULFIDE WITH P-(DIALKYLAMINO)-ANILINE DERIVATIVE AND OXIDIZING AGENT UNDER ACIDIC CONDITIONS | FUJIREBIO INC. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0936466-A2 | Reagent composition for measuring hydrogen sulfide and method for measuring hydrogen sulfide | FUJIREBIO INC. (JP) | 1999-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026080-A1 | Synthesis of N,N-disubstituted-p-phenylenediamine | QDPR, PNMT, DDT | ALDH1A1 1370/4885TSHR 4380/4885MAPK1 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.