Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740663 | 0.92 | ALDH1A1 (0.82) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL6653635 | 0.90 | ALDH1A1 (0.65) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL14596277 | 0.87 | ALDH1A1 (0.62) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL9521212 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL2437580 | 0.84 | ALDH1A1 (0.69) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL7520164 | 0.83 | ALDH1A1 (0.75) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| Hydrochloric Acid SCHEMBL11695056 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL8467252 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL33781 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1CYP3A4TDP1TSHR | |
| SCHEMBL6389743 | 0.82 | ALDH1A1 (0.72) | ALDH1A1MAPK1CYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739079-A1 | Novel bis-para-phenylendiamins joined by a linker arm comprising a sulphur or nitrogen atom and their use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | KRT18, DSP, CDC73 | ALDH1A1 798/4885MAPK1 3482/4885CYP3A4 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.