SCHEMBL6653642

SCHEMBL6653642

CCCCC(CC)Cc1ccc(C(=O)OC(=O)c2ccc(C(=O)OC(=O)c3ccc(CC(CC)CCCC)cc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
LMNA P02545 5/20 0.52
CYP3A4 P08684 4/20 0.52
HSD17B10 Q99714 1/20 0.52
TSHR P16473 7/20 0.49
MAPK1 P28482 3/20 0.49
CA2 P00918 3/20 0.48
BDKRB2 P30411 2/20 0.43
GLA P06280 1/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
PRKCA P17252 1/20 0.40
PRKCD Q05655 1/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
ESR1 P03372 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10800514 0.87 ALDH1A1 (0.49) ALDH1A1LMNACYP3A4HSD17B10TSHR
SCHEMBL6658753 0.87 ALDH1A1 (0.55) ALDH1A1LMNACYP3A4HSD17B10TSHR
SCHEMBL29113362 0.86 LMNA (0.54) ALDH1A1LMNACYP3A4HSD17B10TSHR
SCHEMBL10884804 0.84 KMT2A (0.47) ALDH1A1LMNACYP3A4HSD17B10TSHR
SCHEMBL9700188 0.84 RARB (0.53) ALDH1A1LMNACYP3A4HSD17B10TSHR
SCHEMBL23866983 0.83 LOXL2 (0.51) ALDH1A1LMNACYP3A4HSD17B10TSHR
SCHEMBL17272969 0.83 BDKRB2 (0.44) ALDH1A1LMNACYP3A4HSD17B10TSHR
SCHEMBL153634 0.82 BDKRB2 (0.48) ALDH1A1LMNACYP3A4HSD17B10TSHR
SCHEMBL9487423 0.82 LMNA (0.56) ALDH1A1LMNACYP3A4HSD17B10TSHR
SCHEMBL11658538 0.81 RARB (0.60) ALDH1A1BDKRB2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1592729-A Process for preparing pentacene derivatives 3M INNOVATIVE PROPERTIES CO (US) 2005-03-09 CN disclosed
CN-1582506-A Substituted pentacene semiconductors 3M INNOVATIVE PROPERTIES CO (US) 2005-02-16 CN disclosed
EP-1433211-A2 SUBSTITUTED PENTACENE SEMICONDUCTORS 3M Innovative Properties Company (US) 2004-06-30 EP disclosed
EP-1430008-A2 PROCESS FOR PREPARING PENTACENE DERIVATIVES 3M Innovative Properties Company (US) 2004-06-23 EP disclosed
WO-2003028125-A2 SUBSTITUTED PENTACENE SEMICONDUCTORS 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-04-03 WO disclosed
WO-2003027050-A2 PROCESS FOR PREPARING PENTACENE DERIVATIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-04-03 WO disclosed