Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650132 | 0.83 | HRH3 (0.33) | CYP1A2CYP2D6HRH3KDM4EGUCY1B2 | |
| SCHEMBL6654163 | 0.82 | HRH3 (0.35) | HRH1LMNACYP1A2CYP2D6HRH3 | |
| SCHEMBL6651103 | 0.80 | OPRK1 (0.36) | HRH1HRH4LMNACYP1A2CYP2D6 | |
| SCHEMBL6648694 | 0.78 | TRPM5 (0.38) | HRH1CYP1A2CYP2D6HRH3KDM4E | |
| SCHEMBL6648700 | 0.76 | HRH3 (0.35) | HRH1CYP1A2CYP2D6HRH3KDM4E | |
| SCHEMBL6650011 | 0.76 | DRD4 (0.40) | HRH1HRH4LMNACYP1A2CYP2D6 | |
| SCHEMBL6672328 | 0.76 | TRPM5 (0.32) | HRH1LMNACYP2D6HRH3CHRM2 | |
| SCHEMBL6650451 | 0.74 | LMNA (0.39) | HRH1HRH4LMNACYP1A2CYP2D6 | |
| SCHEMBL6654434 | 0.74 | DRD4 (0.37) | HRH1HRH4LMNACYP1A2CYP2D6 | |
| SCHEMBL6651257 | 0.74 | KMT2A (0.44) | LMNACYP2D6KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |