Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650132 | 0.94 | HRH3 (0.33) | TRPM5HRH3CHRM2SLC6A2SLC6A4 | |
| SCHEMBL6650451 | 0.86 | LMNA (0.39) | TRPM5HRH3LMNACHRM2ADRA2B | |
| SCHEMBL6649435 | 0.83 | OPRK1 (0.37) | HRH3LMNACHRM2ADRA2BSLC6A2 | |
| SCHEMBL6654163 | 0.80 | HRH3 (0.35) | HRH3LMNACHRM2ADRA2BSLC6A2 | |
| SCHEMBL6649371 | 0.79 | HTR1A (0.32) | TRPM5LMNACHRNB2CHRNA4HTR1A | |
| SCHEMBL6651103 | 0.78 | OPRK1 (0.36) | HRH3LMNACHRM2SLC6A2SLC6A4 | |
| SCHEMBL6648700 | 0.76 | HRH3 (0.35) | HRH3CHRM2SLC6A2SLC6A4HRH1 | |
| SCHEMBL6651872 | 0.76 | LMNA (0.36) | TRPM5HRH3LMNACHRM2ADRA2B | |
| SCHEMBL6654437 | 0.76 | HRH1 (0.38) | HRH3LMNACHRM2SLC6A2SLC6A4 | |
| SCHEMBL6650490 | 0.74 | MEN1 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |