Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.53 |
| ▸ | UBE2M | P61081 | 4/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660479 | 0.94 | SLC2A1 (0.55) | CTSSUBE2MDCUN1D1SLC2A1 | |
| SCHEMBL6656366 | 0.94 | CTSS (0.54) | CTSSUBE2MDCUN1D1 | |
| SCHEMBL6656432 | 0.92 | CTSS (0.51) | CTSSUBE2MDCUN1D1SLC2A1 | |
| SCHEMBL6659449 | 0.92 | CTSS (0.55) | CTSSUBE2MDCUN1D1SLC2A1 | |
| SCHEMBL6653280 | 0.91 | DCUN1D1 (0.59) | CTSSUBE2MDCUN1D1 | |
| SCHEMBL7247405 | 0.91 | UBE2M (0.57) | CTSSUBE2MDCUN1D1 | |
| SCHEMBL6658372 | 0.91 | CTSS (0.55) | CTSSUBE2MDCUN1D1 | |
| SCHEMBL6652645 | 0.89 | CTSS (0.52) | CTSSUBE2MDCUN1D1SLC2A1 | |
| SCHEMBL6655095 | 0.89 | CTSS (0.54) | CTSSUBE2MDCUN1D1 | |
| SCHEMBL6650836 | 0.89 | CTSS (0.54) | CTSSUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417202-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | claimed |
| US-20030069276-A1 | Amino piperidine derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | US | claimed |
| WO-2002079186-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069276-A1 | Amino piperidine derivatives | CCR5, CCR2, CXCR4 | CTSS 3409/4885UBE2M 3824/4885DCUN1D1 3697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.