Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16146973 | 0.85 | USP2 (0.45) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL15512638 | 0.82 | USP2 (0.37) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL11506586 | 0.82 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL10847415 | 0.82 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL10007317 | 0.82 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL28454145 | 0.82 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL10849155 | 0.82 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL9329637 | 0.82 | ALDH1A1 (0.55) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL9256250 | 0.82 | USP2 (0.38) | USP2ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL8037794 | 0.82 | TSHR (0.52) | USP2ALDH1A1CYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193005-C | Preparation method for amide | INT FLAVORS & FRAGRANCES INC (US) | 2005-03-16 | — | — | CN | claimed |
| EP-1182191-B1 | Method for making amides | INT FLAVORS & FRAGRANCES INC (US) | 2004-07-14 | — | — | EP | claimed |
| US-6437183-B1 | REACTING NITRILE COMPOUNDS WITH SULFATE COMPOUNDS IN DIOL OR TRIOL SOLVENT | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-08-20 | — | — | US | claimed |
| CN-1340499-A | Preparation method for amide | INT FLAVORS & FRAGRANCES INC (US) | 2002-03-20 | — | — | CN | claimed |
| US-20020028969-A1 | Method for making amides | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-07 | — | — | US | claimed |
| EP-1182191-A1 | Method for making amides | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2002-02-27 | — | — | EP | claimed |
| US-6303817-B1 | MORE SPECIFICALLY A METHOD OF MAKING BUTANAMIDES IN A NEW PROCESS; REACTION OF NITRILE COMPOUNDS AND A SULFATE COMPOUND | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2001-10-16 | — | — | US | claimed |
| US-10407547-B2 | Methods of producing compounds from 5-(halomethyl)furfural | MICROMIDAS, INC. (US) | 2019-09-10 | — | — | US | disclosed |
| US-20170081470-A1 | METHODS OF PRODUCING COMPOUNDS FROM 5-(HALOMETHYL)FURFURAL | MICROMIDAS, INC. (US) | 2017-03-23 | — | — | US | disclosed |
| WO-2015175528-A1 | METHODS OF PRODUCING COMPOUNDS FROM 5-(HALOMETHYL)FURFURAL | MICROMIDAS, INC. (US) | 2015-11-19 | — | — | WO | disclosed |
| CN-1193005-C | Preparation method for amide | INT FLAVORS & FRAGRANCES INC (US) | 2005-03-16 | — | — | CN | disclosed |
| EP-1182191-B1 | Method for making amides | INT FLAVORS & FRAGRANCES INC (US) | 2004-07-14 | — | — | EP | disclosed |
| US-6437183-B1 | REACTING NITRILE COMPOUNDS WITH SULFATE COMPOUNDS IN DIOL OR TRIOL SOLVENT | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-08-20 | — | — | US | disclosed |
| CN-1340499-A | Preparation method for amide | INT FLAVORS & FRAGRANCES INC (US) | 2002-03-20 | — | — | CN | disclosed |
| US-20020028969-A1 | Method for making amides | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-07 | — | — | US | disclosed |
| EP-1182191-A1 | Method for making amides | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2002-02-27 | — | — | EP | disclosed |
| US-6303817-B1 | MORE SPECIFICALLY A METHOD OF MAKING BUTANAMIDES IN A NEW PROCESS; REACTION OF NITRILE COMPOUNDS AND A SULFATE COMPOUND | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2001-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028969-A1 | Method for making amides | NAAA, NIT2, SULT2A1 | USP2 2078/4885ALDH1A1 1296/4885CYP3A4 338/4885 |
| US-10407547-B2 | Methods of producing compounds from 5-(halomethyl)furfural | HDHD5, HPD, DCXR | USP2 1413/4885ALDH1A1 1961/4885CYP3A4 555/4885 |
| US-20170081470-A1 | METHODS OF PRODUCING COMPOUNDS FROM 5-(HALOMETHYL)FURFURAL | HDHD5, HPD, DCXR | USP2 1413/4885ALDH1A1 1961/4885CYP3A4 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.