SCHEMBL665496

SCHEMBL665496

C=C(C)C(=O)OCC([SiH3])(OC(C)C)OC(C)C

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
THRB P10828 1/20 0.38
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396763 0.79 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL580728 0.76 THRB (0.47) TSHRTHRBALDH1A1
SCHEMBL393525 0.75 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL8850932 0.75 TSHR (0.57) TSHRTHRBALDH1A1
SCHEMBL15864506 0.74 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL9615552 0.72 TSHR (0.48) TSHRTHRBALDH1A1
SCHEMBL664175 0.72 THRB (0.40) TSHRTHRBALDH1A1
SCHEMBL57880 0.72 TSHR (0.52) TSHRTHRBALDH1A1
SCHEMBL23494007 0.72 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL8850972 0.72 TSHR (0.53) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2941460-B1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2017-11-22 EP disclosed
US-9683125-B2 One-component, curable coating compositions, processes for making and using them, and coatings and articles prepared with them BASF COATINGS GMBH (DE) 2017-06-20 US disclosed
US-20150337159-A1 One-Component, Curable Coating Compositions, Processes For Making And Using Them, And Coatings And Articles Prepared With Them BASF COATINGS GMBH (DE) 2015-11-26 US disclosed
EP-2941460-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF Coatings GmbH (DE) 2015-11-11 EP disclosed
US-8865851-B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith BASF COATINGS GMBH (DE) 2014-10-21 US disclosed
WO-2014106552-A1 ONE -COMPONENT, CURABLE COATING COMPOSITION, PROCESSES FOR MAKING AND USING THEM, AND COATINGS AND ARTICLES PREPARED WITH THEM BASF COATINGS GMBH (DE) 2014-07-10 WO disclosed
US-20120045586-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS AND THE USE THEREOF BASF COATINGS GMBH (DE) 2012-02-23 US disclosed