SCHEMBL580728

SCHEMBL580728

C=C(C)C(=O)OCC([SiH3])(OCC)OCC

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TSHR P16473 4/20 0.42
ALDH1A1 P00352 4/20 0.37
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15864506 0.86 TSHR (0.47) THRBTSHRALDH1A1
SCHEMBL17922843 0.82 THRB (0.53) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL20135807 0.81 THRB (0.50) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL396763 0.81 TSHR (0.44) THRBTSHRALDH1A1
SCHEMBL664175 0.81 THRB (0.40) THRBTSHRALDH1A1
SCHEMBL986236 0.80 TSHR (0.53) THRBTSHRALDH1A1
SCHEMBL268178 0.79 THRB (0.48) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL1779171 0.79 THRB (0.48) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL486168 0.78 TSHR (0.56) THRBTSHRALDH1A1
SCHEMBL21066735 0.77 TSHR (0.58) THRBTSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115895353-A Preparation method of FEVE coating 江苏考普乐新材料股份有限公司 2023-04-04 CN claimed
EP-2414466-B1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF COATINGS GMBH (DE) 2013-10-16 EP claimed
EP-1833865-B1 CROSS-LINKABLE, SILANE-MODIFIED COPOLYMERS WACKER CHEMIE AG (DE) 2010-03-17 EP claimed
US-20080145676-A1 free radical copolymerization of a vinyl ester or acrylate monomer with a post-crosslinkable ethylenically unsaturated silane such as methacryloyloxymethylmethoxydimethylsilane; aqueous dispersion or water-redispersible powders; high storage stability with rapid cure; adhesive, cements, binder, coating WACKER CHEMIE AG (DE) 2008-06-19 US claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
EP-3585851-B1 AIR AND WATER BARRIER ARTICLE INCLUDING INELASTIC POROUS LAYER 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-01 EP disclosed
US-12403671-B2 Roll including air and water barrier article and method of using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-09-02 US disclosed
EP-3108076-B1 EASY TO APPLY AIR AND WATER BARRIER ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-03-26 EP disclosed
US-12227936-B2 Tape, article including tape and composite layer, and related methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-02-18 US disclosed
EP-3337867-B1 AIR AND WATER BARRIER ARTICLE WITH POROUS LAYER AND LINER 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-04-10 EP disclosed
EP-3107712-B1 SELF SEALING ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-09-20 EP disclosed
CN-115975444-A FEVE coating 江苏考普乐新材料股份有限公司 2023-04-18 CN disclosed
EP-1746134-A1 CURABLE COMPOSITION WITH IMPROVED CURABILITY AND ADHESIVENESS Kaneka Corporation (JP) 2007-01-24 EP disclosed
EP-1746133-A1 CURABLE COMPOSITION IMPROVED IN ADHESIVENESS Kaneka Corporation (JP) 2007-01-24 EP disclosed
EP-1746135-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2007-01-24 EP disclosed
EP-1736511-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2006-12-27 EP disclosed
EP-1734079-A1 SINGLE-COMPONENT CURABLE COMPOSITION Kaneka Corporation (JP) 2006-12-20 EP disclosed
EP-1731574-A1 SINGLE-COMPONENT CURABLE COMPOSITION KANEKA CORPORATION (JP) 2006-12-13 EP disclosed
EP-1731573-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 THRB 4533/4885TSHR 4650/4885ALDH1A1 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.