SCHEMBL396763

SCHEMBL396763

C=C(C)C(=O)OCC([SiH3])(OC)OC

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.43
THRB P10828 1/20 0.41
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3206542 0.87 TSHR (0.35) TSHRALDH1A1THRB
SCHEMBL580728 0.81 THRB (0.47) TSHRALDH1A1THRB
SCHEMBL734093 0.81 THRB (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL664175 0.80 THRB (0.40) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL665496 0.79 TSHR (0.48) TSHRALDH1A1THRB
SCHEMBL393525 0.79 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL9558554 0.79 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL14576566 0.79 ALDH1A1 (0.40) TSHRALDH1A1
SCHEMBL419928 0.78 TSHR (0.51) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL15864506 0.78 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2189485-B1 Polyurethane composition comprising alpha-silane having anisostropic material properties SIKA TECHNOLOGY AG (CH) 2011-02-16 EP claimed
EP-1833865-B1 CROSS-LINKABLE, SILANE-MODIFIED COPOLYMERS WACKER CHEMIE AG (DE) 2010-03-17 EP claimed
US-20080145676-A1 free radical copolymerization of a vinyl ester or acrylate monomer with a post-crosslinkable ethylenically unsaturated silane such as methacryloyloxymethylmethoxydimethylsilane; aqueous dispersion or water-redispersible powders; high storage stability with rapid cure; adhesive, cements, binder, coating WACKER CHEMIE AG (DE) 2008-06-19 US claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
EP-3585851-B1 AIR AND WATER BARRIER ARTICLE INCLUDING INELASTIC POROUS LAYER 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-01 EP disclosed
US-12403671-B2 Roll including air and water barrier article and method of using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-09-02 US disclosed
EP-3941952-B1 THERMOPLASTIC ELASTOMER COMPOSITION HAVING LOW DENSITY AND GOOD MECHANICAL PROPERTIES BY USING UNCOATED HOLLOW GLASS SPHERES KRAIBURG TPE GMBH & CO KG (DE) 2025-04-30 EP disclosed
EP-3108076-B1 EASY TO APPLY AIR AND WATER BARRIER ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-03-26 EP disclosed
US-12227936-B2 Tape, article including tape and composite layer, and related methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-02-18 US disclosed
EP-3337867-B1 AIR AND WATER BARRIER ARTICLE WITH POROUS LAYER AND LINER 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-04-10 EP disclosed
EP-3107712-B1 SELF SEALING ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-09-20 EP disclosed
EP-1749857-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2007-02-07 EP disclosed
EP-1746134-A1 CURABLE COMPOSITION WITH IMPROVED CURABILITY AND ADHESIVENESS Kaneka Corporation (JP) 2007-01-24 EP disclosed
EP-1746133-A1 CURABLE COMPOSITION IMPROVED IN ADHESIVENESS Kaneka Corporation (JP) 2007-01-24 EP disclosed
EP-1746135-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2007-01-24 EP disclosed
EP-1736511-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2006-12-27 EP disclosed
EP-1734079-A1 SINGLE-COMPONENT CURABLE COMPOSITION Kaneka Corporation (JP) 2006-12-20 EP disclosed
EP-1731574-A1 SINGLE-COMPONENT CURABLE COMPOSITION KANEKA CORPORATION (JP) 2006-12-13 EP disclosed
EP-1731573-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885THRB 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.