Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 6/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17396368 | 0.77 | CPA3 (0.39) | KCNN4 | |
| SCHEMBL8659893 | 0.76 | TRPA1 (0.37) | KIF11KCNN4KDM4ELMNAMAPK1 | |
| SCHEMBL2719854 | 0.76 | KIF11 (0.36) | KIF11 | |
| SCHEMBL938787 | 0.74 | TAAR1 (0.43) | TAAR1HTR2AKIF11KCNN4KDM4E | |
| SCHEMBL29460275 | 0.74 | RIPK1 (0.41) | TAAR1KIF11MAPK1 | |
| SCHEMBL10770500 | 0.74 | MEN1 (0.38) | KIF11 | |
| SCHEMBL8086291 | 0.74 | KIF11 (0.34) | KIF11KCNN4KDM4ELMNAMAPK1 | |
| SCHEMBL10006934 | 0.73 | KCNN4 (0.43) | KIF11KCNN4KDM4ELMNAMAPK1 | |
| SCHEMBL10007041 | 0.73 | KCNN4 (0.43) | KIF11KCNN4KDM4ELMNAMAPK1 | |
| SCHEMBL11192499 | 0.73 | TAAR1 (0.41) | TAAR1HTR2AKIF11KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435954-A1 | HIGH PURITY AMLODIPINE BENZENESULFONATE AND A PROCESS FOR ITS PREPARATION | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003004025-A1 | HIGH PURITY AMLODIPINE BENZENESULFONATE AND A PROCESS FOR ITS PREPARATION | LEK PHARMACEUTICAL AND CHEMICAL COMPANY D.D. (DE) | 2003-01-16 | — | — | WO | disclosed |
| EP-0305929-B1 | Membranes with bound oligonucleotides and peptides | MILLIPORE CORP (US) | 1996-04-10 | — | — | EP | disclosed |
| US-4923901-A | Membranes with bound oligonucleotides and peptides | MILLIPORE CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0341298-A1 | FLUORESCENT POLY(ARYLPYRIDINE) RARE EARTH CHELATES | Baxter Diagnostics Inc. (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0305929-A2 | Membranes with bound oligonucleotides and peptides | MILLIPORE CORPORATION (US) | 1989-03-08 | — | — | EP | disclosed |