Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12832472 | 0.87 | ATM (0.60) | ATMHSP90AA1LCKANPEPMDM4 | |
| SCHEMBL11591050 | 0.82 | DRD2 (0.54) | ATMANPEPDRD2HTR2AHTR2B | |
| SCHEMBL12247210 | 0.80 | ALDH1A1 (0.50) | DRD2HTR2AHTR2BALDH1A1L3MBTL1 | |
| SCHEMBL9128812 | 0.80 | ATM (0.47) | ATMHSP90AA1LCKANPEPMDM4 | |
| SCHEMBL28744982 | 0.80 | L3MBTL1 (0.42) | ANPEPMDM4TP53ALDH1A1L3MBTL1 | |
| SCHEMBL17845245 | 0.79 | LMNA (0.49) | ATMHSP90AA1LCKANPEPMDM4 | |
| SCHEMBL12780367 | 0.79 | CXCL8 (0.58) | ATMHSP90AA1LCKCXCL8ALDH1A1 | |
| SCHEMBL27285058 | 0.79 | MAPK1 (0.58) | ATMHSP90AA1TP53CXCL8L3MBTL1 | |
| SCHEMBL14058700 | 0.78 | POLB (0.57) | ATMHSP90AA1LCKALDH1A1L3MBTL1 | |
| SCHEMBL24963550 | 0.77 | ATM (0.52) | ATMALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-11-25 | — | — | US | disclosed |
| EP-1427705-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003026415-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | DDT, NRDC, NOXO1 | ATM 4778/4885HSP90AA1 2962/4885LCK 3122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.