Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658791 | 0.91 | KCNH2 (0.46) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6662202 | 0.85 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6662302 | 0.83 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6660405 | 0.83 | KCNH2 (0.45) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6664855 | 0.80 | MAOB (0.52) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6657379 | 0.79 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6658616 | 0.79 | MEN1 (0.51) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6656945 | 0.77 | MEN1 (0.48) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6655172 | 0.76 | KMT2A (0.49) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6658355 | 0.76 | ALOX5 (0.41) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |