Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13488660 | 0.84 | LMNA (0.48) | KMT2ATSHRTDP1MAPTSMN1; SMN2 | |
| SCHEMBL6417963 | 0.83 | ALDH1A1 (0.51) | KMT2ATSHRTDP1MAPTSMN1; SMN2 | |
| SCHEMBL6662302 | 0.83 | MAPT (0.46) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6659859 | 0.82 | ALDH1A1 (0.47) | KMT2ATSHRTDP1MAPTSMN1; SMN2 | |
| SCHEMBL6658616 | 0.79 | MEN1 (0.51) | KMT2ATSHRTDP1MAPTSMN1; SMN2 | |
| SCHEMBL6657379 | 0.79 | MAPT (0.53) | KMT2ATSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6658355 | 0.78 | ALOX5 (0.41) | KMT2AMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6662202 | 0.77 | MAPT (0.60) | KMT2ATDP1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6664855 | 0.77 | MAOB (0.52) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6656820 | 0.76 | DRD2 (0.54) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | claimed |
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |