Acediasulfone

Acediasulfone

SCHEMBL6656166

Nc1ccc(S(=O)(=O)c2ccc(NCC(=O)O)cc2)cc1.[NaH]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.55
PKM P14618 1/20 0.55
PRMT1 Q99873 6/20 0.54
CYP3A4 P08684 3/20 0.52
CYP2C9 P11712 2/20 0.52
LMNA P02545 1/20 0.52
MPO P05164 1/20 0.52
TSHR P16473 1/20 0.52
HTR6 P50406 1/20 0.52
SETD7 Q8WTS6 1/20 0.49
MAPK1 P28482 1/20 0.47
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47
CA12 O43570 3/20 0.47
CA9 Q16790 3/20 0.47
CA14 Q9ULX7 1/20 0.47
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acediasulfone SCHEMBL143660 0.98 CYP2C19 (0.57) CYP2C19PKMPRMT1CYP3A4CYP2C9
Acediasulfone SCHEMBL27874832 0.89 CYP2C19 (0.55) CYP2C19PKMPRMT1CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL11148769 0.86 MAPT (0.55) CYP2C19PKMCYP3A4CYP2C9LMNA
Hydrochloric Acid SCHEMBL7148684 0.86 MAPT (0.55) CYP2C19PKMCYP3A4CYP2C9LMNA
SCHEMBL1312570 0.86 MAPT (0.55) CYP2C19PKMCYP3A4CYP2C9LMNA
Acediasulfone SCHEMBL30530977 0.84 CYP2C19 (0.55) CYP2C19PKMPRMT1CYP3A4CYP2C9
SCHEMBL8637752 0.80 CA1 (0.68) CA1CA2CA12CA9CA14
SCHEMBL15067141 0.78 CA1 (0.49) LMNATSHRCA1CA2CA12
Dapsone SCHEMBL2321694 0.77 HTR6 (0.67) CYP2C19PKMPRMT1CYP3A4CYP2C9
SCHEMBL1042560 0.77 CYP3A4 (0.55) CYP2C19PKMPRMT1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2953624-B1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS LUODA PHARMA LTD (IE) 2019-08-21 EP claimed
US-20160000748-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS Luoda Pharma Limited (IE) 2016-01-07 US claimed
US-20150366797-A1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS Luoda Pharma Limited (IE) 2015-12-24 US claimed
EP-2953624-A1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS Luoda Pharma Pty Ltd (AU) 2015-12-16 EP claimed
EP-2953623-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS Luoda Pharma Pty Ltd (AU) 2015-12-16 EP claimed
WO-2014121342-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS LUODA PHARMA PTY LIMITED (AU) 2014-08-14 WO claimed
US-11491105-B2 Methods of treating microbial infections, including mastitis Luoda Pharma Limited (IE) 2022-11-08 US disclosed
EP-2953623-B1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS LUODA PHARMA LTD (IE) 2021-06-30 EP disclosed
EP-2953624-B1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS LUODA PHARMA LTD (IE) 2019-08-21 EP disclosed
US-9943500-B2 Methods of treating topical microbial infections LUODA PHARMA PTY LTD (AU) 2018-04-17 US disclosed
US-20160000748-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS Luoda Pharma Limited (IE) 2016-01-07 US disclosed
US-20150366797-A1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS Luoda Pharma Limited (IE) 2015-12-24 US disclosed
EP-2953623-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS Luoda Pharma Pty Ltd (AU) 2015-12-16 EP disclosed
EP-2953624-A1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS Luoda Pharma Pty Ltd (AU) 2015-12-16 EP disclosed
WO-2014121342-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS LUODA PHARMA PTY LIMITED (AU) 2014-08-14 WO disclosed
EP-1438942-A1 An otorhinological drug delivery device Schering Oy (FI) 2004-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000748-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS TSLP, CCL11, IL17A CYP2C19 2855/4885PKM 4058/4885PRMT1 4743/4885
US-20150366797-A1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS LCT, TSLP, MLEC CYP2C19 3581/4885PKM 4368/4885PRMT1 4181/4885
US-11491105-B2 Methods of treating microbial infections, including mastitis LCT, TSLP, MLEC CYP2C19 3581/4885PKM 4368/4885PRMT1 4181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.