SCHEMBL6657992

SCHEMBL6657992

CC(C)C[C@H](NC(=O)[C@H](C)N)C(=O)NCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
LMNA P02545 1/20 0.46
PTGS2 P35354 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LAP3 P28838 3/20 0.43
CTSL P07711 3/20 0.41
CTSB P07858 3/20 0.41
CTSS P25774 2/20 0.41
CTSK P43235 2/20 0.41
PTGS1 P23219 1/20 0.41
GSTK1 Q9Y2Q3 1/20 0.41
ECE1 P42892 1/20 0.41
MME P08473 3/20 0.40
ACE P12821 1/20 0.40
CPA1 P15085 1/20 0.40
ACE2 Q9BYF1 1/20 0.40
CAPN1 P07384 2/20 0.40
CAPN9 O14815 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3495921 1.00 ALDH1A1 (0.46) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL3495919 1.00 ALDH1A1 (0.46) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL29498158 0.93 MMP8 (0.43) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL31410871 0.91 ALDH1A1 (0.39) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL29906328 0.91 EGFR (0.42) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL29250266 0.89 ALDH1A1 (0.37) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL29394144 0.89 MAPT (0.44) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL30051701 0.87 ALDH1A1 (0.43) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL5176099 0.87 CTSL (0.38) ALDH1A1MAPTLAP3CTSLCTSB
SCHEMBL7201733 0.87 CTSL (0.38) ALDH1A1MAPTLAP3CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118079030-A Drug-loaded polymer nano micelle and preparation method and application thereof 郑州大学 2024-05-28 CN claimed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 CN claimed
CN-104755482-A Functionalized 9-bromo-camptothecin derivatives NERVIANO MEDICAL SCIENCES SRL 2015-07-01 CN claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
US-20250257338-A1 GLYCOPROTEIN HAVING REDUCED NUMBER OF MANNOSE-6-PHOSPHATES JCR PHARMACEUTICALS CO., LTD. (JP) 2025-08-14 US disclosed
EP-4512892-A1 GLYCOPROTEIN HAVING REDUCED NUMBER OF MANNOSE-6-PHOSPHATES JCR Pharmaceuticals Co., Ltd. (JP) 2025-02-26 EP disclosed
CN-118079030-A Drug-loaded polymer nano micelle and preparation method and application thereof 郑州大学 2024-05-28 CN disclosed
WO-2023204202-A1 GLYCOPROTEIN HAVING REDUCED NUMBER OF MANNOSE-6-PHOSPHATES JCRファーマ株式会社 2023-10-26 WO disclosed
CN-110003337-B IL17RA single domain antibody, nucleic acid and kit 深圳普瑞金生物药业股份有限公司 2023-05-09 CN disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 CN disclosed
CN-104755482-A Functionalized 9-bromo-camptothecin derivatives NERVIANO MEDICAL SCIENCES SRL 2015-07-01 CN disclosed
EP-1436317-A1 MOLECULES THAT BLOCK VIRAL INFECTIVITY AND METHODS OF USE THEREOF TRIPEP AB (SE) 2004-07-14 EP disclosed
WO-2003024995-A1 MOLECULES THAT BLOCK VIRAL INFECTIVITY AND METHODS OF USE THEREOF TRIPEP AB (SE) 2003-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP ALDH1A1 3596/4885MAPT 3330/4885LMNA 1538/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD ALDH1A1 4110/4885MAPT 4191/4885LMNA 3184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.