Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSB | P07858 | 4/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.37 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5176099 | 1.00 | CTSL (0.38) | CTSLCTSBCTSSCTSKMMP8 | |
| SCHEMBL6657992 | 0.87 | ALDH1A1 (0.46) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL3495921 | 0.87 | ALDH1A1 (0.46) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL3495919 | 0.87 | ALDH1A1 (0.46) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL7198213 | 0.86 | OPRM1 (0.39) | CTSLCTSBCTSSCTSKMMP8 | |
| SCHEMBL7198220 | 0.86 | OPRM1 (0.39) | CTSLCTSBCTSSCTSKMMP8 | |
| SCHEMBL14008029 | 0.85 | ALDH1A1 (0.55) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL7204776 | 0.85 | PAX8 (0.41) | MMP8DPP4 | |
| SCHEMBL22188067 | 0.85 | DPP4 (0.39) | CTSSCTSKDPP4ALDH1A1MAPT | |
| SCHEMBL7204771 | 0.85 | PAX8 (0.41) | MMP8DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030050242-A1 | Protein polymerization inhibitors and methods of use | TRIPEP AB (SE) | 2003-03-13 | — | — | US | disclosed |
| US-20020091086-A1 | Peptides that block viral infectivity and methods of use thereof | VAHLNE ANDERS (SE) | 2002-07-11 | — | — | US | disclosed |
| EP-1207897-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING TRIPEPTIDES | TRIPEP AB (SE) | 2002-05-29 | — | — | EP | disclosed |
| US-6258932-B1 | TRIPEPTIDE OF DEFINED AMINO ACID SEQUENCE AND HAVING A C-TERMINAL AMIDE; VIRICIDES; TREATMENT AND PREVENTION OF HUMAN IMMUNODEFICIENCY VIRUS | TRIPEP AB (BE) | 2001-07-10 | — | — | US | disclosed |
| WO-2001010457-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING TRIPEPTIDES | TRIPEP AB (SE) | 2001-02-15 | — | — | WO | disclosed |