SCHEMBL6659162

SCHEMBL6659162

C[Si](C)=C1C=CC(C2c3ccccc3-c3ccccc32)=C1[Zr]

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.36
GPR3 P46089 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7203180 0.79 HTR2A (0.39) HTR2AGPR3
SCHEMBL8089189 0.78 HTR2A (0.34) HTR2AGPR3
Hydrochloric Acid SCHEMBL7592112 0.72 POLB (0.34) HTR2AGPR3
SCHEMBL6652896 0.71 HTR2A (0.34) HTR2AGPR3
SCHEMBL4912027 0.65 MAPT (0.61) HTR2AGPR3
Hydrochloric Acid SCHEMBL7205244 0.64 HTR2A (0.37) HTR2A
SCHEMBL7157162 0.62 GPR3 (0.34) HTR2AGPR3
SCHEMBL9852665 0.60 NOS3 (0.37) HTR2AGPR3
SCHEMBL8906349 0.60 HTR2A (0.35) HTR2AGPR3
Hydrochloric Acid SCHEMBL7203692 0.59 HTR2A (0.38) HTR2AGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1257587-B1 HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS DOW GLOBAL TECHNOLOGIES INC (US) 2004-06-23 EP claimed
EP-1257587-A2 HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS THE DOW CHEMICAL COMPANY (US) 2002-11-20 EP claimed
WO-2001004164-A2 HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS THE DOW CHEMICAL COMPANY (US) 2001-01-18 WO claimed
EP-1257587-A2 HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS THE DOW CHEMICAL COMPANY (US) 2002-11-20 EP disclosed
WO-2001004164-A2 HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS THE DOW CHEMICAL COMPANY (US) 2001-01-18 WO disclosed