SCHEMBL7157162

SCHEMBL7157162

C[Si]1(C)[C]2C=CC(C3c4ccccc4-c4ccccc43)=C21

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.34
HTR2A P28223 1/20 0.34
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6652896 0.64 HTR2A (0.34) GPR3HTR2ABCHEACHE
SCHEMBL17321727 0.63 HTR2A (0.40) GPR3HTR2A
SCHEMBL4912027 0.63 MAPT (0.61) GPR3HTR2ABCHEACHEPOLB
SCHEMBL8366223 0.62 POLB (0.35) GPR3HTR2APOLB
SCHEMBL6659162 0.62 HTR2A (0.36) GPR3HTR2A
SCHEMBL9852665 0.62 NOS3 (0.37) GPR3HTR2AACHE
SCHEMBL8906349 0.62 HTR2A (0.35) GPR3HTR2ABCHEACHEPOLB
SCHEMBL27885617 0.61 HTR2A (0.52) GPR3HTR2ABCHEACHEPOLB
SCHEMBL6659159 0.61 GPR3 (0.32) GPR3HTR2A
Hydrochloric Acid SCHEMBL7203692 0.61 HTR2A (0.38) GPR3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889059-B1 Catalyst based on monoazadiene metal complexes BAYER AG (DE) 2003-02-12 EP disclosed
US-20020052446-A1 Composition based on monofluorometal complexes BAYER AKTIENGESELLSCHAFT (DE) 2002-05-02 US disclosed
US-5965678-A Catalyst system based on monoazadiene metal complexes BAYER AG (DE) 1999-10-12 US disclosed
EP-0889059-A1 Catalyst based on monoazadiene metal complexes BAYER AG (DE) 1999-01-07 EP disclosed