Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846516 | 0.65 | SLC6A2 (0.33) | NOS3NOS2NOS1SLC6A2SLC6A4 | |
| SCHEMBL8906349 | 0.63 | HTR2A (0.35) | SLC6A2SLC6A4SLC6A3HTR2AACHE | |
| SCHEMBL7157162 | 0.62 | GPR3 (0.34) | HTR2AACHEGPR3 | |
| Hydrochloric Acid SCHEMBL8905301 | 0.61 | HTR2A (0.33) | SLC6A2SLC6A4SLC6A3HTR2ACYP19A1 | |
| SCHEMBL8941781 | 0.61 | ACHE (0.59) | NOS3NOS2NOS1TYMSHTR2A | |
| SCHEMBL4912027 | 0.61 | MAPT (0.61) | HTR2ACYP19A1ACHEGPR3 | |
| SCHEMBL6659162 | 0.60 | HTR2A (0.36) | HTR2AGPR3 | |
| SCHEMBL8366223 | 0.60 | POLB (0.35) | HTR2AGPR3 | |
| SCHEMBL40599 | 0.59 | GPR3 (0.52) | SLC6A2SLC6A4SLC6A3HTR2AACHE | |
| SCHEMBL29641604 | 0.59 | GPR3 (0.52) | SLC6A2SLC6A4SLC6A3HTR2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407870-A2 | Process for preparing cycloolefin polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-16 | — | — | EP | disclosed |