Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7203180 | 0.75 | HTR2A (0.39) | HTR2AGPR3 | |
| Hydrochloric Acid SCHEMBL3783189 | 0.75 | HTR2A (0.35) | HTR2ACYP3A4GPR3 | |
| Hydrochloric Acid SCHEMBL2353823 | 0.72 | HTR2A (0.33) | HTR2A | |
| Hydrochloric Acid SCHEMBL7205244 | 0.72 | HTR2A (0.37) | HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL7206464 | 0.71 | HTR6 (0.30) | HTR2A | |
| Bromide SCHEMBL7205884 | 0.71 | HTR2A (0.35) | HTR2AGPR3 | |
| Hydrochloric Acid SCHEMBL8927357 | 0.70 | HTR2A (0.32) | HTR2AKDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL7209697 | 0.69 | HTR2A (0.38) | HTR2AMAPT | |
| Hydrochloric Acid SCHEMBL8390027 | 0.69 | HTR2A (0.34) | HTR2AMAPT | |
| Hydrochloric Acid SCHEMBL7205527 | 0.69 | HTR2A (0.34) | HTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891382-B1 | ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION | TEIJIN LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6388032-B1 | SEPARATION BY FILTRATION | TEIJIN LIMITED (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1028128-A1 | CYCLOOLEFIN POLYMER REDUCED IN CATALYST RESIDUE CONTENT, USE THEREOF, AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | disclosed |
| EP-0891382-A1 | ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION | TEIJIN LIMITED (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998033830-A1 | ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION | TEIJIN LIMITED (JP) | 1998-08-06 | — | — | WO | disclosed |