SCHEMBL6660060

SCHEMBL6660060

OB(O)Oc1nc2ccccc2s1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
PTGS1 P23219 6/20 0.46
PTGS2 P35354 6/20 0.46
ALDH1A1 P00352 3/20 0.44
ALOX15 P16050 2/20 0.44
HPGD P15428 2/20 0.44
ADRA2A P08913 1/20 0.44
FBP1 P09467 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
DRD2 P14416 1/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
DRD1 P21728 1/20 0.44
MC5R P33032 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30721098 1.00 CYP1A2 (0.49) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL30241094 0.81 SMN1; SMN2 (0.36) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL5391779 0.78 PTGS1 (0.55) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL6736271 0.78 CYP1A2 (0.60) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL6001878 0.76 PTGS1 (0.51) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL13283703 0.75 PTGS1 (0.50) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL20733630 0.75 PTGS1 (0.54) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL347497 0.75 SMN1; SMN2 (0.54) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL11684240 0.74 SMN1; SMN2 (0.56) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL3938450 0.74 PTGS1 (0.50) CYP1A2CYP3A4CYP2D6CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150376085-A1 ANTHRACENE COMPOUND, METHOD FOR PREPARING THE SAME, USE THEREOF AND ORGANIC LIGHT EMITTING DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-12-31 US claimed
CN-113563323-A Benzothiazolyl biaryl compounds, preparation method and application 上海凌达生物医药有限公司 2021-10-29 CN disclosed
CN-108530473-A With the compound of amyloid beta specific binding 南京中硼联康医疗科技有限公司 2018-09-14 CN disclosed
CN-108440584-A It is used to prepare the preparation method of the intermediate of the compound specifically bound with amyloid beta 南京中硼联康医疗科技有限公司 2018-08-24 CN disclosed
CN-108395446-A With the preparation method of the compound of amyloid beta specific binding 南京中硼联康医疗科技有限公司 2018-08-14 CN disclosed
CN-108276435-A It is used to prepare the preparation method of the intermediate of the compound specifically bound with amyloid beta 南京中硼联康医疗科技有限公司 2018-07-13 CN disclosed
CN-108239100-A It is used to prepare compound, the preparation method and applications of the compound specifically bound with amyloid beta 南京中硼联康医疗科技有限公司 2018-07-03 CN disclosed
CN-108187044-A For eliminating the neutron capture treatment system of amyloid beta 南京中硼联康医疗科技有限公司 2018-06-22 CN disclosed
CN-106674265-B Compounds that specifically bind to β amyloid 南京中硼联康医疗科技有限公司 2018-03-09 CN disclosed
CN-106730414-B Neutron capture therapy system for eliminating beta amyloid 南京中硼联康医疗科技有限公司 2017-10-10 CN disclosed
CN-106730414-A Neutron capture therapy system for eliminating beta amyloid 南京中硼联康医疗科技有限公司 2017-05-31 CN disclosed
CN-106674265-A Compounds that specifically bind to amyloid beta 南京中硼联康医疗科技有限公司 2017-05-17 CN disclosed
US-20150376085-A1 ANTHRACENE COMPOUND, METHOD FOR PREPARING THE SAME, USE THEREOF AND ORGANIC LIGHT EMITTING DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-12-31 US disclosed
CN-105078978-A Heterocyclic compounds and uses thereof INTELLIKINE LLC 2015-11-25 CN disclosed
CN-102573846-B Heterocyclic compounds and their use INTELLIKINE, INC. (US) 2015-10-07 CN disclosed
CN-103130741-A Organic semiconductor material containing naphthyl anthracene and preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2013-06-05 CN disclosed
CN-102573846-A Heterocyclic compounds and their use INTELLIKINE INC 2012-07-11 CN disclosed
EP-1444981-A1 INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS Mikoshiba, Katsuhiko (JP) 2004-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376085-A1 ANTHRACENE COMPOUND, METHOD FOR PREPARING THE SAME, USE THEREOF AND ORGANIC LIGHT EMITTING DEVICE CYP2C9, AHR, AOC2 CYP1A2 21/4885CYP3A4 68/4885CYP2D6 189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.