Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL666066

N.O.O[Si](O)(O)O.[AlH3]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL68853 0.93
Water SCHEMBL5049052 0.93
Ammonia Solution, Strong SCHEMBL463347 0.93
Ammonia Solution, Strong SCHEMBL4004001 0.93
Water SCHEMBL10760068 0.93
Water SCHEMBL19250733 0.93
Water SCHEMBL5933728 0.93
Water SCHEMBL28937047 0.93
Water SCHEMBL29152887 0.93
Ammonia Solution, Strong SCHEMBL27713883 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10392807-B2 Non-black EPDM roof membranes with improved weathering Firestone Building Products Co., LLC (US) 2019-08-27 US disclosed
US-20180179759-A1 NON-BLACK EPDM ROOF MEMBRANES WITH IMPROVED WEATHERING AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2018-06-28 US disclosed
US-9915069-B1 Non-black EPDM roof membranes with improved weathering Firestone Building Products Co., LLC (US) 2018-03-13 US disclosed
US-9802391-B2 Non-black rubber membranes Firestone Building Products Co., LLC (US) 2017-10-31 US disclosed
US-20160221309-A1 NON-BLACK RUBBER MEMBRANES AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2016-08-04 US disclosed
US-9309674-B2 Non-black rubber membranes Firestone Building Products Co., LLC (US) 2016-04-12 US disclosed
US-20150038031-A1 NON-BLACK RUBBER MEMBRANES AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2015-02-05 US disclosed
US-8791193-B2 Non-black rubber membranes FIRESTONE BUILDING PRODUCTS COMPANY, LLC (US) 2014-07-29 US disclosed
US-8367760-B1 Non-black rubber membranes FIRESTONE BUILDING PRODUCTS COMPANY, LLC (US) 2013-02-05 US disclosed
US-20120045953-A1 NON-BLACK RUBBER MEMBRANES AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2012-02-23 US disclosed
WO-2007084614-A2 HAIR GROWTH FORMULA SAKURA PROPERTIES, LLC (US) 2007-07-26 WO disclosed
US-20060280892-A1 Rubber membranes that are useful for roofing and related methods BFS DIVERSIFIED PRODUCTS, LLC 2006-12-14 US disclosed
US-20060210515-A1 HAIR GROWTH FORMULA SAKURA PROPERTIES, LLC 2006-09-21 US disclosed