Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 5/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337832 | 0.70 | SLC18A3 (0.47) | — | |
| SCHEMBL6337835 | 0.70 | SLC18A3 (0.47) | — | |
| SCHEMBL6469082 | 0.69 | KCNH2 (0.36) | — | |
| SCHEMBL14713128 | 0.64 | SIGMAR1 (0.36) | KDM4EMAPT | |
| SCHEMBL6340314 | 0.64 | SIGMAR1 (0.44) | — | |
| SCHEMBL7075491 | 0.62 | TSHR (0.41) | ALDH1A1GAAMAPT | |
| SCHEMBL6660001 | 0.61 | DRD2 (0.37) | KDM4EALDH1A1MAPT | |
| SCHEMBL19558206 | 0.60 | MAOA (0.38) | ALDH1A1MAPT | |
| SCHEMBL3606126 | 0.57 | CREBBP (0.32) | PRKCDPRKCGPRKCA | |
| SCHEMBL3606128 | 0.57 | CRBN (0.36) | PRKCDPRKCGPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470126-A1 | N-SUBSTITUTED SPIROPIPERIDINE COMPOUNDS AS LIGANDS FOR ORL-1 RECEPTOR | PFIZER INC. (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064425-A1 | N-SUBSTITUTED SPIROPIPERIDINE COMPOUNDS AS LIGANDS FOR ORL-1 RECEPTOR | PFIZER JAPAN INC. (JP) | 2003-08-07 | — | — | WO | disclosed |