SCHEMBL6661385

SCHEMBL6661385

Nc1ncc(NC=O)c(N)n1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7247622 0.84 BCL6 (0.38) DHFR
SCHEMBL7944560 0.82 ADORA1 (0.33) DHFR
SCHEMBL7274718 0.80 LMNA (0.41)
SCHEMBL23450302 0.76 NUDT1 (0.35)
SCHEMBL4716502 0.74
SCHEMBL27932742 0.73 RPS6KA3 (0.48)
SCHEMBL27948438 0.73 ADORA1 (0.43)
SCHEMBL8928297 0.73 MEN1 (0.33)
SCHEMBL27710395 0.71 ALDH1A1 (0.41)
SCHEMBL3182502 0.69 DHFR (0.43) DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105753798-A Novel gas production compound 北京理工大学 2016-07-13 CN disclosed
CN-105190309-A Non-invasive method for measuring oxidative stress and oxidative damage from skin biomarkers PROCTER & GAMBLE 2015-12-23 CN disclosed
WO-2004011606-A3 MACROMOLECULAR PROTECTION ASSAY ALFA WASSERMAN INC (US) 2004-05-06 WO disclosed
EP-1078102-A1 METHOD FOR IDENTIFYING NUCLEIC ACID MOLECULES Epicentre Technologies Corporation (US) 2001-02-28 EP disclosed
WO-1999058717-A1 METHOD FOR IDENTIFYING NUCLEIC ACID MOLECULES EPICENTRE TECHNOLOGIES CORPORATION (US) 1999-11-18 WO disclosed