Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661385 | 0.82 | DHFR (0.33) | DHFR | |
| SCHEMBL28062887 | 0.81 | KDM5A (0.33) | KDM5A | |
| SCHEMBL7247622 | 0.79 | BCL6 (0.38) | ADORA1ADORA2ADHFR | |
| SCHEMBL23450302 | 0.71 | NUDT1 (0.35) | — | |
| SCHEMBL1703076 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL27932742 | 0.69 | RPS6KA3 (0.48) | ADORA1ADORA2A | |
| SCHEMBL27948438 | 0.69 | ADORA1 (0.43) | ADORA1ADORA2A | |
| SCHEMBL30019416 | 0.69 | KDM5A (0.33) | KDM5A | |
| SCHEMBL7274718 | 0.68 | LMNA (0.41) | — | |
| SCHEMBL13300377 | 0.68 | L3MBTL1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242599-B1 | Process for the preparation of guanine | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2001-06-05 | — | — | US | claimed |